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Alprazolam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy.<>6 - The FDA label advises that the physician should periodically reassess the usefulness of the drug.<> - Alprazolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression.<>8 - Alprazolam is also often prescribed with instances of hypersomnia and co-morbid sleep deficits.
Panic disorder
Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks.<> - However, it is not a first line treatment since the development of selective serotonin reuptake inhibitors, and alprazolam is no longer recommended in Australia for the treatment of panic disorder due to concerns regarding tolerance, dependence and abuse.<>0 - Evidence supporting the effectiveness of alprazolam in treating panic disorder has been limited to 4 to 10 weeks. However, people with panic disorder have been treated on an open basis for up to 8 months without apparent loss of benefit.<> - <>9 -
In the United States, alprazolam is FDA-approved for the treatment of panic disorder with or without agoraphobia.<> - Alprazolam is recommended by the World Federation of Societies of Biological Psychiatry (WFSBP) for treatment-resistant cases of panic disorder where there is no history of tolerance or dependence.<>0 -
Anxiety disorders
Anxiety associated with depression is responsive to alprazolam. Demonstrations of the effectiveness by systematic clinical study are limited to 4 months duration for anxiety disorder.<> - However, the research into antidepressant properties of alprazolam is of poor quality and only assessed the short-term effects of alprazolam against depression.<>1 - In one study, some long term, high-dosage users of alprazolam developed reversible depression.<>2 - In the US, alprazolam is FDA-approved for the management of anxiety disorders (a condition corresponding most closely to the APA Diagnostic and Statistical Manual DSM-IV-TR diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. In the UK, alprazolam is recommended for the short-term treatment (2–4 weeks) of severe acute anxiety.<>9 - <>3 - <>4 -
Nausea due to chemotherapy
Alprazolam may be used in combination with other medications for chemotherapy-induced nausea and vomiting.<>6 -
Pregnancy and lactation
Benzodiazepines cross the placenta, enter into the fetus and are also http://bakkerij-museum.nl/wp-content/ai1ec_static/buy-xanax-online/ - cheap xanax excreted with breast milk. The use of benzodiazepines during pregnancy or lactation has potential risks. The use of alprazolam in pregnancy is believed to be associated with congenital abnormalities. Diazepam and chlordiazepoxide have a better safety profile in pregnancy than alprazolam.
Women who are pregnant or are planning on becoming pregnant should avoid starting alprazolam.<>5 - Use in the last trimester may cause fetal drug dependence and withdrawal symptoms in the post-natal period<>6 - as well as neonatal flaccidity and respiratory problems.<>7 - However, in long-term users of benzodiazepines abrupt discontinuation due to concerns of teratogenesis has a high risk of causing extreme withdrawal symptoms and a severe rebound effect of the underlying mental health disorder. Spontaneous abortions may also result from abrupt withdrawal of psychotropic medications including benzodiazepines.<>8 -
Benzodiazepines, including alprazolam, are known to be excreted in human milk.<>9 - Chronic administration of diazepam to nursing mothers has been reported to cause their infants to become lethargic and to lose weight.<>0 - <>1 -
Contraindications
Benzodiazepines require special precaution if used in children and in alcohol- or drug-dependent individuals. Particular care should be taken in pregnant or elderly patients, patients with substance abuse history, particularly alcohol dependence and patients with comorbid psychiatric disorders.<>2 - Use of alprazolam should be avoided or carefully monitored by medical professionals in individuals with the following conditions: myasthenia gravis, acute narrow-angle glaucoma, severe liver deficiencies (e.g., cirrhosis), severe sleep apnea, pre-existing respiratory depression, marked neuromuscular respiratory weakness including unstable myasthenia gravis, acute pulmonary insufficiency, chronic psychosis, hypersensitivity or allergy to alprazolam or other drugs in the benzodiazepine class, borderline personality disorder (may induce suicidality and dyscontrol).<>4 - <>3 - <>4 - <>5 -
Like all central nervous system depressants, including alcohol, http://www.sillmwr.com/sponsorsads/buy-valium-onine/ - valium online sverige alprazolam in larger-than-normal doses can cause significant deterioration in alertness, combined with increased feelings of drowsiness, especially in those unaccustomed to the drug's effects.<>6 - People driving or conducting activities that require vigilance should exercise caution in using alprazolam or any other depressant until they know how it affects them.
Elderly individuals should be cautious in the use of alprazolam due to the possibility of increased susceptibility to side-effects, especially loss of coordination and drowsiness.<>0 -
Adverse effects


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